How to (not) lose your mind — a (not so) original approach on Alzheimer’s disease (1)

Did you know that Alzheimer’s disease is in fact not one but a group of three diseases. Type one (inflammation type) is characterized by loss of ability to store new information, but the long term memory and the ability to speak, calculate, spell and write is retained. Type 2 is characterized by loss of trophic support, and by loss of ability to store new information, but the long term memory and the ability to speak, calculate, spell and write is retained. Inflammatory markers are not high in this case, they can even be lower than normal. You can have both type 1 and type 2 in the same time later in life. This may run in the family. Type 3 is toxic (vile) and appears usually in people carrying the common ApoE3 allele rather than ApoE4. Does not run in the family. Usually strikes at age 40–50, following grat stress, with cognitive difficulties involving numbers , speech and organizing skills. Short term, long term and procedural memory (how to do simple or complex things) is affected. Exposure to toxic compounds (heavy metals, mycotoxins from mold) seems to be also one of the factors increasing the risk.

Type 1 starts at age 40–50 if you have one copy of ApoE4 allele, or at age 50–60 if you have two copies of ApoE4. No copies of ApoE4 — starts around 60–70. Type 2 initiates a decade later than type one, given the same variation of ApoE4.

(Extra information here — Apolipoprotein E (APOE) is a protein involved in the metabolism of fats in the…